Identification of key residues in Debaryomyces hansenii carbonyl reductase for highly productive preparation of (S)-aryl halohydrins.
نویسندگان
چکیده
Key residues of Debaryomyces hansenii carbonyl reductase in the determination of the reducing activity towards aryl haloketones were identified through combinatorial mutation of conserved residues. This study provides a green and efficient biocatalyst for the synthesis of (S)-aryl halohydrins.
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ورودعنوان ژورنال:
- Chemical communications
دوره 51 86 شماره
صفحات -
تاریخ انتشار 2015